Resources for medication reconciliation

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Safety and Quality > Our Work > Medication Safety > Medication reconciliation > Resources for medication reconciliation

Resources to support medication reconciliation include:

	GoR*
Vaginal hysteropexy is equally effective as vaginal hysterectomy with apical suspension and is associated with reduced blood loss and operating time	B
Vaginal hysterectomy with apical suspension has a lower reoperation rate for prolapse than abdominal sacro-hysteropexy	B
Salpingectomy ↓ risk of ovarian cancer in women retaining ovaries at the time of hysterectomy	B
Bilateral salpingo-oophorectomy (BSO) at hysterectomy in post-menopausal women ↓ rate of ovarian cancer without ↑ morbidity	B
SC with hysterectomy is not recommended due to high rate of mesh exposure	B
Supracervical hysterectomy has a lower rate of mesh exposure than hysterectomy and SC	B
Sacro-hysteropexy has a ↑ reoperation rate for prolapse than SC with hysterectomy	C
Supracervical hysterectomy has ↑ rate of recurrent POP compared to SC and hysterectomy	C
Although data is not complete, vaginal based apical suspensions should generally be considered for uterine prolapse reserving SC for recurrent or post hysterectomy prolapse	C

Vault prolapse (post hysterectomy)	GoR*
Sacral colpopexy (SC) has significant anatomical and functional advantages when compared with a broad group of vaginal surgery (± mesh)	A
Transvaginal apical mesh confers no advantage when compared to native tissue repairs	A
Uterosacral and sacrospinous colpopexy have similar efficacy for apical prolapse	B
Laparoscopic SC has advantages over both robotic and open approach however the learning curve with the laparoscopic approach is significant	B
Sacrospinous ligament fixation and abdominal sacrocolpopexy have equivalent success rates	B
Vaginal apical suspensions appropriate in those not suitable for SC (Delphi)	C

Isolated rectocele	GoR*
Posterior Colporrhaphy (PC) is the procedure of choice	B
Levatorplasty associated with high rate of dyspareunia	B
PC reduced prolapse with equal functional outcome compared to transanal approach	B
Fascial plication is superior to site specific posterior vaginal repair	C
No evidence demonstrating benefit for synthetic or biological graft	C
Those with combined vaginal prolapse and bowel symptoms benefit from colorectal and gynaecologist collaboration	C
Ventral rectopexy and vaginal graft is unnecessary for isolated rectocele	D

Isolated cystocele	GoR*
Anterior Colporrhaphy (AC) is generally recommended however permanent synthetic mesh could be considered for recurrent prolapse if women understand the risk/benefit profile	A
Non-autologous grafts offer no significant advantage over AC	B
Native tissue repair is recommended, but carries a higher risk of prolapse recurrence	B
Mesh repairs are associated with higher risk of adverse events	B
Mesh repair may be considered for recurrent prolapse after patient informed and accepts the risk/benefit	B
Adjunctive fascial slings may be used to prevent recurrent prolapse in high grade cystoceles	C

Prolapse surgery and lower urinary tract functions	GoR*
Women with POP + SUI
Surgery for POP + SUI shows a higher rate of cure of urinary incontinence in the short term	A
Combined POP + SUI surgery carries a higher risk of adverse events	A
Women with POP + occult SUI
POP + occult SUI equals POP and continence surgery (consider staged procedure)	B
Women with POP + occult SUI are at risk of development of incontinence post POP repair alone, with some proceeding to additional SUI surgery at a later date	A
Combined POP + SUI surgery reduces the risk of post operative incontinence	A
Combined POP + SUI surgery increases the risk of adverse events	A
Continent women with POP
POP without occult SUI does not require concomitant continence surgery	B
Women with POP and Overactive Bladder (OAB)
There is low level (inconsistent) evidence to suggest that operative repair can improve OAB symptoms	C

	GoR*
Perioperative physiotherapy did not reduce the rate of recurrent prolapse	A
Stage 3 or Stage 4 prolapse	B
Low volume surgeons have ↑ rate of complications compared to high volume surgeons	B
Patient age < 60 years	C
Less experienced surgeons have higher rates of recurrent prolapse after transvaginal surgery	C
Preoperative widened genital hiatus or levator defects on urinary signs and symptoms: data are inconclusive	D

Retropubic versus transobturator mid-urethral sling	GoR*
In the short-term there are similar success rates for retropublic and transobturator	A
Obturator tapes slightly quicker, with less blood loss, bladder perforation and voiding dysfunction difficulties. Most of these differences were small and the complications are readily able to be managed.	A
However in the medium term (>5 years) the reoperation for recurrent SUI greater in obturator group and a small number developed groin pain (3-4%) that is difficult to treat.	B
Retropubic considered as the preferred procedure with transobturator reserved for those patients with a hostile abdomen	C

Retropubic versus transobturator mid-urethral sling	GoR*
In the short‐term there are similar success rates for retropubic and transobturator mid urethral slings	A
Obturator tapes are slightly quicker, with less blood loss, bladder perforation and voiding dysfunction difficulties. Most of these differences were small and the complications are readily able to be managed.	A
However in the medium term (>5 years) the reoperation for recurrent SUI greater in obturator group and a small number developed groin pain (3-4%) that is difficult to treat.	B
Retropubic considered as the preferred procedure with transobturator reserved for those patients with a hostile abdomen	C

Pubovaginal (fascial) sling	GoR*
Similar success rates compared to MUS with longer operating time and possibly higher voiding dysfunction; fascial sling has lower rates of chronic pelvic pain, no risk of erosion or extrusion, and higher rates of post‐operative morbidity	B
Lower rate of bladder perforation during surgery compared to MUS.	B
Fascial sling has higher patient satisfaction and treatment success compared to colposuspension	B
Involves a longer operation, post‐operative hospital stay (2–3 days) and recovery period than MUS	B
Consider in women wishing to avoid mesh‐related complications	–

	GoR*
Inferior outcomes to pubovaginal slings for primary repair, possibly with less voiding dysfunction	B
Outcomes similar or slightly less than synthetic MUS however longer operating time and recovery, slower return to activities of daily living and more prolapse in medium term	B
Laparoscopic approach when performed same technique as open has similar success rate with less morbidity than open approach	B
Lower rates of success, with higher retreatment rates, when compared to pubovaginal slings for primary repair	B

	GoR*
May be a useful option for recurrent SUI with a well supported urethra	B
Greater symptomatic improvement was observed with surgical treatments, although the advantage needs to be balanced against risk of intervention	C
Consider in women wishing to avoid mesh‐related complications	–

	GoR*
The most extensively researched option for SUI establishing efficacy and safety profile	A
As effective or more effective than colposuspension or pubovaginal sling with less perioperative and post-operative morbidity	B
Recommended surgical treatment female SUI	C