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On 17 August 2021, the Commission released the Cataract Clinical Care Standard.
On 26 May 2021, the Commission released the Management of Peripheral Intravenous Catheters Clinical Care Standard.
On 24 November 2021, the Commission released the new national Acute Anaphylaxis Clinical Care Standard.
On 28 April 2021, the Commission released the Fourth Australian Atlas of Healthcare Variation.
On 9 September 2021, the Commission released the updated Delirium Clinical Care Standard (2021).
On 21 April 2021, the Commission announced the introduction of Australia's first Third and Fourth Degree Perineal Tears Clinical Care Standard.
On 27 August 2021, the Commission released the Fourth Australian report on antimicrobial use and resistance in human health (AURA 2021).