ACSQHC-ARCR-102

Penile cancer is a rare malignancy in Australia with an incidence of 0.6 in 100,000 men, and has high morbidity and mortality. It carries a significant burden of disease and psychosocial impact for men affected. There is a paucity of comprehensive local epidemiological data and management guidelines. The registry aims to address this gap by creating a centralised database to study local risk factors, treatment effectiveness, and outcomes. The APCR is a national, multicentre prospective study, utilising a combination of respective and prospective data. We focus on men above 18 years of age, who have been diagnosed or previously treated for penile cancer, including those with recurrences or on active surveillance. The primary objective is to establish a health-care provider based penile cancer clinical registry to improve the local evidence base, and bridge local and international interdisciplinary gaps. The primary outcome is to map demographic and tumour characteristics in Australia. Secondary outcomes include understanding HPV infection rates, analyse health disparities in management, and investigate long term outcomes of surgical interventions, lymph node interventions and chemotherapy for penile cancer.