Staphylococcus aureus bloodstream infection (SABSI) prevention resources

Healthcare-associated Staphylococcus aureus bloodstream infection (SABSI) is commonly associated with significant morbidity and mortality. Resources to support prevention of these infections in health service organisations play an important role; information on strategies to support these activities, and access to a range of resources, are included on this page. 

Both long-standing, and recent, literature support the value of sustained infection prevention and control practices in reducing the incidence of preventable SABSI.

Measures to prevent SABSI in health care include:

  • Hand hygiene to minimise transmission of microorganisms on healthcare worker’s hands
  • Optimal insertion, management and removal of intravascular devices
  • Preoperative methicillin-resistant Staphylococcus aureus (MRSA) screening
  • Perioperative antimicrobial prophylaxis and targeted, appropriate antimicrobial therapy
  • Optimisation of surgical site management
  • Feedback on infection surveillance and reporting to clinicians.

The Australian Health Ministers’ Advisory Council endorsed a new national benchmark for healthcare-associated SABSI for public hospital reporting, which was implemented from 1 July 2020.

The current benchmark is 1.0 per 10,000 patient days.

To support implementation of the revised SABSI benchmark, the Commission has developed a compendium of resources to support SABSI prevention.

The Commission has also produced the following resources to assist with SABSI surveillance:

All states and territories will have a range of existing resources to further support SABSI prevention, such as maintaining skin integrity, wound care and invasive device management; check your state and territory health authority website.

If your organisation has relevant resources to contribute to this compendium, please email