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Carbapenemase-producing Enterobacterales

Enterobacterales is the name given to a family of bacteria that normally lives in the human gut. Some of these bacteria produce enzymes, called carbapenemases, which stop antimicrobials from working against the bacteria. Carbapenemase-producing Enterobacterales (CPE) are resistant to most types of antibiotics. There is a high mortality rate associated with infections caused by CPE due to limited treatment options.

Recommendations for the control of CPE

Surveillance of CPE in Australia

CPE is currently monitored as one of the critical antimicrobial resistances (CARs) in CARAlert.

Key facts about CPE in Australia:

  • The prevalence of CPE is increasing. CPE increased by 37% between 2021 and 2022 
  • In 2023, almost one-half of the CARs reported to CARAlert were CPE 
  • Over half the CPE cultures collected by CARAlert were from blood culture specimens.

For more information see AURA 2023 and CARAlert annual reports and data updates.

Find more in our resource library
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