Antimicrobial stewardship
Antimicrobial Stewardship includes a range of activities that promote and support optimal antimicrobial prescribing and use. We have a range of resources and information to support health professionals and services with antimicrobial stewardship and improve the safe and appropriate use of antimicrobials.
Antimicrobials refer to all antibiotics, antivirals, antifungals, and antiparasitic agents. They treat and prevent infections caused by bacteria, viruses, fungi, parasites and other microorganisms.
Antimicrobial Stewardship (AMS) programs help to decrease inappropriate antimicrobial use and prevent and contain antimicrobial resistance.
What is Antimicrobial Stewardship?
Antimicrobial Stewardship programs are run by a team of health professionals within hospitals and health care settings and involve a range of activities and strategies that optimise antimicrobial use and decrease antimicrobial resistance.
These activities can include:
- auditing the use of antimicrobials
- providing feedback and advice to health professionals on alternative options to antimicrobials
- overseeing and managing antimicrobials
- monitoring antimicrobial prescribing patterns to identify trends and areas for improvement
- raising awareness on antimicrobial resistance.
Our Preventing and Controlling Infections Standard requires all health service organisations to have an Antimicrobial Stewardship program.
Our Antimicrobial Stewardship in Australian Health Care book provides detailed advice and steps on running AMS programs.
View our Antimicrobial Stewardship in Australian Health Care book (AMS Book)
We also provide resources to help health services successfully implement their Antimicrobial Stewardship programs and meet the requirements of our Preventing and Controlling Infections Standards and Antimicrobial Stewardship Clinical Care Standard.
Why is Antimicrobial Stewardship important?
Inappropriate use of antimicrobials contribute to antimicrobial resistance, where microorganisms develop the ability to survive exposure to antimicrobial agents.
People who have infections caused by antimicrobial resistant microorganisms are more likely to experience ineffective treatment, recurrent infection, delayed recovery, or even death.
Antimicrobial Stewardship programs help to decrease inappropriate antimicrobial use and prevent and contain antimicrobial resistance.
Antimicrobial Stewardship in primary care
The primary care sector has an important role to play in improving the safe and appropriate use of antimicrobials and reducing patient harm and risk of antimicrobial resistance in Australia.
There are a range of resources available to support AMS implementation and antimicrobial use in primary care settings.
Resources for primary care
- Antimicrobial Stewardship in Australian Health Care (AMS Book) – refer to Chapter 13 – Role of general practice in antimicrobial stewardship
- Access the Therapeutic Guidelines
- Antimicrobial Shortages
- Antibiotic shortages - Clinicians working in the Aboriginal and Torres Strait Islander health sector
- Safety considerations during benzathine benzylpenicillin (Billin L-A) supply disruption)
- Options for implementation of AMS primary care - Aboriginal Community Controlled Health Services
- Options for implementation of AMS primary care - Allied Health including Optometry and Podiatry Practices
- Options for implementation of AMS primary care - community health services
- Options for implementation of AMS primary care - Dental Practice
- Options for implementation of AMS in primary care - General Practice
- Options for implementation of AMS in primary care - community pharmacy
- Asymptomatic bacteriuria – 2020
- Improving antimicrobial prescribing through selective reporting of antimicrobials
- Decision support tools for specific conditions
- RACGP - Antimicrobial Stewardship Position Statement
- RACGP - Standards for general practice residential aged care
- NACCHO Medicines Management Guidelines
- PSA Guidelines for pharmacists supporting Aboriginal and Torres Strait Islander peoples with Medicines Management
- Antibiotic prescribing in primary care: Therapeutic Guidelines summary table 2025
Antimicrobial Stewardship and children
Antimicrobial Stewardship is important in the care of children because antimicrobials can have long term consequences for their health.
Antimicrobials are often inappropriately prescribed for children and at higher rates than other age groups. Studies have shown almost 40% of antimicrobial prescriptions for children are not prescribed in accordance with clinical guidelines. Early antibiotic exposure is associated with increased risk of chronic disease later in life, such as allergy, atopic dermatitis, coeliac disease, diabetes, and obesity.
Resources for children
- Antimicrobial Stewardship in Australian Health Care (AMS Book) – refer to Chapter 14: Antimicrobial stewardship in the care of children
- AURA 2023: Fifth Australian report on antimicrobial use and resistance in human health - Report – refer to Chapter 3: Antimicrobial use and appropriateness for the section on prescribing rates in different age groups.
- Antimicrobial Shortages
- Antibiotic shortages - Clinicians working in the Aboriginal and Torres Strait Islander health sector
- Decision support tools for specific conditions
- Paediatric Antimicrobial Stewardship Good Practice Recommendations
- Multinational consensus antimicrobial stewardship recommendations for children managed in hospital settings
- Kids Dose - a network of paediatric clinician researchers regarding therapeutics for the most common diseases of childhood
Resources and links for Antimicrobial Stewardship program support
There are a range of Australian and international resources to support antimicrobial stewardship programs in health service organisations, aged care and primary care.
Commission resources
- Preventing and Controlling Infections Standard
- Options for implementation of Antimicrobial Stewardship in a range of facilities
- Specification for a Hospital Cumulative Antibiogram 2019
- Australian Commission on Safety and Quality in Health Care and the Council of Presidents of Medical Colleges (CPMC) Joint Statement - Antimicrobial Prescribing
- CPMC 2020 AMR Statement - Supporting Infographic - February 2021
- Antimicrobial Stewardship Clinical Care Standard
- Community antimicrobial use report – August 2025
- What is antimicrobial resistance and how can we prevent it?
- Access to Therapeutic Guidelines
- Surgical Antibiotic Prophylaxis Improving Practice Infographic
- Approaches to surgical site infection surveillance: For acute care settings in Australia
Antimicrobial use surveillance programs
- National Antimicrobial Prescribing Survey (NAPS)
- National Antimicrobial Usage Surveillance Program (NAUSP)
Participation in NAPS and NAUSP and use of data from these programs to improve antimicrobial prescribing is one option that may assist with meeting the antimicrobial stewardship (AMS) actions of the National Safety and Quality Health Service Preventing and Controlling Infections Standard and the Aged Care Quality Standards.
Australian resources and links
- Australian Group on Antimicrobial Resistance
- Australian Society for Antimicrobials
- Australasian Society for Infectious Diseases
- Communicable Diseases Network Australia
- National Antibiotic Allergy Network
- National Antimicrobial Resistance Strategy
- National Centre for Antimicrobial Stewardship
- Therapeutic Guidelines: Antibiotic
International resources and links
- World Health Organization – Antimicrobial Resistance
- Centers for Disease Prevention and Control – Antibiotic Prescribing and Use
- UK Health Security Agency – Antimicrobial resistance
- NICE – Antimicrobial Stewardship
- Scottish Antimicrobial Prescribing Group
- Video – Why is Antimicrobial Stewardship important?
- Video – What do we do when antibiotics don’t work anymore?
Online learning modules
The Commission has a range of online learning modules on antimicrobials, aimed at prescribers in their early stages of clinical practice, nurse practitioners, hospital pharmacists, and university students. The modules address specific areas where antimicrobial use in hospitals and primary care settings can be supported to further improve prescribing practices.
Access our online learning modules
AMR Awareness activities
World AMR Awareness Week (WAAW) is a global campaign to raise awareness and improve understanding on AMR and promote best practices to reduce the spread of AMR. It is celebrated from 18 – 24 November each year.
We support WAAW by providing resources and coordinating initiatives across the week.
We have a range of resources and links to support World AMR Awareness Week in Australia.
International resources and links
- Antibiotic Awareness Week - Canada
- Centers for Disease Control and Prevention (CDC) - US Antibiotic Awareness Week
- European Centre for Disease Prevention and Control (ECDC) - European Antibiotic Awareness
- New Zealand Ministry of Health - Resources for antimicrobial resistance
- National Collaborating Centre for Infectious Diseases (NCCID) – Canada
- UK Health Security Agency - Keep Antibiotics Working Campaign
- World Health Organization (WHO) Campaign - World Antibiotic Awareness Week